吸入辅助装置在哮喘和慢性阻塞性肺疾病治疗中的应用  

Application of add-on devices for inhalation in the treatment of asthma and chronic obstructive pulmonary disease

作　　者：张海霞[1,2,3] 邓万定[2,3] 周建平[1] 金方[2,3] 

机构地区：[1]中国药科大学药剂学教研室,南京210009 [2]中国医药工业研究总院 [3]上海医药工业研究院上海呼吸系统药物工程技术研究中心,上海200437

出　　处：《世界临床药物》2011年第11期696-701,共6页World Clinical Drug

基　　金：上海市重点科技攻关专项资助(项目编号10dz2251400)

摘　　要：以儿童与老年人为主体的特定人群,熟练掌握吸入产品的使用技术有一定难度,尤其是在压力定量吸入气雾剂(pMDI)的使用中,辅助装置的使用较为关键。吸入辅助装置可降低pMDI使用过程中对"揿压并吸入"的协同要求,还能增加药物在肺部的沉积剂量,提高疗效。本文简要综述吸入辅助装置在哮喘和慢性阻塞性肺疾病(COPD)治疗中的应用与吸入辅助装置的推广使用情况。For a certain group of people,such as children and the elderly,they are not able to master the specific inhalation method,especially the technique of pMDI inhalation.Therefore,add-on devices for inhalation are necessary.pMDI add-on devices can decrease the need for coordination between actuation and inhalation.Furthermore,they are also able to increase lung deposition and improve therapeutic effects.This review gives a brief introduction to application of add-on devices for inhalation in the treatment of asthma and chronic obstructive pulmonary disease（COPD）,and it also covers promotion of the use of add-on devices.

关 键 词：PMDI 吸入辅助装置 管道储雾器 单向储雾器 逆流装置 面罩 抗静电储雾器 

分 类 号：R974[医药卫生—药品] R944[医药卫生—药学]