慢性乙型肝炎患者生存质量评价及其中医辨证关系  

Evaluation on the quality of life of chronic hepatitis B and its relationship with the syndrome type of traditional Chinese medicine

作　　者：张玮[1] 王俐琼[1] 刘一博[1] 

机构地区：[1]上海中医药大学附属龙华医院肝科,上海200030

出　　处：《中国肝脏病杂志（电子版）》2008年第1期31-34,共4页Chinese Journal of Liver Diseases：Electronic Version

摘　　要：目的评价慢性乙型肝炎患者的生存质量,并探讨中医各证型与生存质量的相关性。方法采用横断面调查,应用世界卫生组织生存质量测定简表(WHOQOL-BRIEF)和慢性肝病问卷(CLDQ)调查200例慢性乙型肝炎患者的生存质量,并与50例正常人进行比较。结果慢性乙型肝炎患者的生存质量较差,与正常对照组相比差异有统计学意义(P<0.01),且中医各证型间生存质量存在差异(P<0.05或P<0.01),以肝郁脾虚证患者生存质量最低(P<0.01)。结论慢性乙型肝炎患者生存质量较差,并与中医辨证分型具有相关性。Objective To evaluate the quality of life H8 (QOL) among patients with chronic hepatitis B and to approach the relationship between the syndrome type of traditional Chinese medicine (TCM) and QOL.Methods As a cross-sectional study,200 patients with chronic hepatitis B were tested by determination sheet for QOL from the World Health Organization (WHOQOL-BRIEF) and the chronic liver disease questionnaire (CLDQ).Meanwhile it was compared with 50 healthy adults.Results The QOL of patients with chronic hepatitis B is lower than normal controls and the discrepancy has statistical significance (P < 0.05),also it exists among all types of syndrome in TCM (P < 0.01 or P < 0.05),and patients with syndrome of liver-Qi stagnation and spleen deficiency had the lowest QOL (P < 0.01).Conclusions The quality of life among patients with chronic hepatitis B is lower and correlated closely with the types of syndrome in traditional Chinese medicine.

关 键 词：慢性乙型肝炎 生存质量 辨证分型 

分 类 号：R259[医药卫生—中西医结合]