聚乳酸衍生物的设计与合成及性能研究  

On the Study of Design, Synthesis and the Performance of Polylactic Acid Derivative

作　　者：李倩[1] 刘永和[1] 张雪锋[2] 

机构地区：[1]邵阳学院生物与化学工程系,湖南邵阳422000 [2]上海交通大学化学化工学院,上海200240

出　　处：《邵阳学院学报（自然科学版）》2008年第4期61-64,共4页Journal of Shaoyang University：Natural Science Edition

摘　　要：合成聚丙交酯,先用BOC氨基酸的羧基(BOC为叔丁基氧羰基)与聚丙交酯末端的羟基进行酯化反应,然后用甲酸除掉BOC基团.最后用葡萄糖内酯与氨基反应,在聚丙交酯的末端引入了亲水性的葡萄糖基团,最终实现了对聚丙交酯的亲水性修饰.SyTonthesize the poly(L-lactide)(PolyLA),First,let the BOC amino-acid of the carboxyl and the hydroxyl at the end of Poly(L-lactide) react with each other.Then formaldehyde was used to get ride of BOC-group.And at last,let glucose-lactones and amino-group react with each other.At the end of Poly LA hydrophilic Glucose-groups are pulled in.Consequently,this procedure has realized the hydrophilic modification of poly LA.

关 键 词：聚乳酸 亲水修饰 合成 

分 类 号：O631.3[理学—高分子化学]