Non-invasive Prenatal Gene Diagnosis: Progress through Cell-free Fetal DNA and RNA in Maternal Plasma and Urine  

作　　者：GUO Xun-yang, GUO Yi-bin ( Department of Medical Genetics, Zhongshan School of Medicine, SUN Yat-Sen University, Guangzhou 510080, China ) 

出　　处：《中山大学学报（医学科学版）》2008年第S2期140-142,共3页Journal of Sun Yat-Sen University:Medical Sciences

基　　金：National natural science funding(ID:30772069);CMB partial funding(2003)

摘　　要：Non-invasive prenatal gene diagnosis has been developed rapidly in the recent years, and numerous medical researchers are focusing on it. Such techniques could not only achieve prenatal diagnosis accurately, but also prevent tangential illness in fetuses and thus, reduce the incidence of diseases. Moreover, it is non-invasive prenatal gene diagnosis that prevents potential threaten and danger to both mothers and fetuses. Therefore, it is welcomed by clinical gynecologist and obstetrian, researchers of medical genetics, and especially, pregnancies. This review article touches briefly on the advanced development of using cell-free DNA, RNA in maternal plasma and urine for non-invasive prenatal gene diagnosis.Non-invasive prenatal gene diagnosis has been developed rapidly in the recent years, and numerous medical researchers are focusing on it. Such techniques could not only achieve prenatal diagnosis accurately, but also prevent tangential illness in fetuses and thus, reduce the incidence of diseases. Moreover, it is non-invasive prenatal gene diagnosis that prevents potential threaten and danger to both mothers and fetuses. Therefore, it is welcomed by clinical gynecologist and obstetrian, researchers of medical genetics, and especially, pregnancies. This review article touches briefly on the advanced development of using cell-free DNA, RNA in maternal plasma and urine for non-invasive prenatal gene diagnosis.

关 键 词：NON-INVASIVE prenatal gene diagnosis CELL-FREE fetal DNA and RNA DNA and RNA detection MATERNAL URINE MATERNAL plasma 

分 类 号：R714.5[医药卫生—妇产科学]