上海市不同人群SARS血清流行病学研究  

Serum Epidemiological Study on Severe Acute Respiratory Syndrome in Shanghai

作　　者：李燕婷[1] 康来仪[1] 张爱香[1] 金汇明[1] 沈荣明[1] 沈薇娟[1] 周妍[1] 朱奕奕[1] 何懿[1] 顾宝柯[1] 张胜年[1] 

机构地区：[1]上海市疾病预防控制中心,200336

出　　处：《中国病毒病杂志》2005年第1期10-12,共3页Chinese Journal of Viral Diseases

摘　　要：目的　分析本市不同人群SARS抗体水平,为今后防治提供依据。方法　采用酶联免疫吸附试验(ELISA)检测SARS病人、疑似、留观病人、密切接触者、医务人员和社区一般人群等血清中SARS特异性抗体并进行分析比较。结果　SARS病人抗体阳性率为87 5 0 % ,其他非SARS病人、密切接触者和社区一般人群抗体阳性率分别为0 . 5 8%、0 . 3 0 %和0 .5 4% ,输血者为0 .48%。SARS病人与非SARS病人及其他不同人群抗体阳性率差异有统计学意义,有暴露史与无暴露史人群、有外出史与无外出史人群以及各年龄组之间抗体阳性率无明显差异。结论　上海市不同人群SARS隐性感染低,其抗体可持续半年以上。低年龄组人群无感染状况值得研究。Objective To analyze antibody levels of severe acute respiratory syndrome in different people in Shanghai for future prevention. Methods To detect and analyze SARS serum antibody of clinical confirmed patients, suspect patients, clinical observational patients, contactors, doctors and community people with Enzyme-Linked Immunosorbnent Assay (ELISA). Results Masculine ratio of SARS patients was 87.50%, masculine ratios of non-patients, contactors, blood transfusion people and community people were 0.58%,0.30%,0.48% and 0.54% respectively. There was significant difference between SARS patients and others. But exposure history, going-out history and age showed no significant difference. Conclusions Inapparent infectious ratio of different people in Shanghai is low and their antibody could last out for more than half a year. The phenomenon of no infection in low-age group child is good for research in future.

关 键 词：严重急性呼吸综合征 血清学 感染 

分 类 号：R511.9[医药卫生—内科学]