Cajal间质细胞和胃肠动力  

Interstitial cell of Cajal and gastrointestinal peristalsis

作　　者：王征[1] 沈洲姬[2] 

机构地区：[1]浙江医学高等专科学校,浙江杭州310053 [2]浙江大学医学院附属邵逸夫医院,浙江杭州310016

出　　处：《浙江医学教育》2005年第3期38-40,共3页Zhejiang Medical Education

摘　　要：胃肠道正常运动依赖慢波及神经递质的调控。慢波是由一类特殊的间质细胞激发的,称为Cajal间质细胞(nterstitial Cells of Cajal,ICC)。胃肠道的ICC根据解剖位置的不同可分为ICCMY、ICCIM、ICCDMP、ICCSM及ICCSEP。ICCIM在胃肠道的神经传导中有重要作用。ICC产生慢波的机制目前尚不甚清楚,该过程可能与IP3依赖性钙离子的释放有关。Normal gastrointestinal peristalsis depends on the control of slow waves and neurotransmitters.Slow waves are generated by some kind of special interstitial cell,which is called Inerstitial Cells of Cajal(ICC).According to the difference of anatomic location,ICCs in the gastrointestinal tract has six types,which were named as ICCMY,ICCIM,ICCDMP,ICCSM, ICCSEP and ICCIM respectively.ICCM has an important role on neuron transmission in the gastrointestinal tract.The mechanism how generate slow waves is not clear now.The process maybe is related with the release of IP3-dependent Calcium ion.

关 键 词：Cajal间质细胞(ICC) 慢波 胃肠动力 起搏电位 神经控制 

分 类 号：R333[医药卫生—人体生理学]