骨腱结合部损伤模型建立及伤后低强度循环载荷对愈合的影响  

Effects of Early Return to Training on Bone-tendon Junction Post-acute Micro-injury Healing

作　　者：王琳[1] 高维纬[1] 熊开宇[1] 刘宁[1] 王博[1] 梁戈[1] 徐斌[1] 温春毅[2] 吕维加[2] 

机构地区：[1]北京体育大学,北京100084 [2]香港大学创伤与矫形外科学系

出　　处：《沈阳体育学院学报》2011年第5期60-63,共4页Journal of Shenyang Sport University

基　　金：国家自然科学基金支持项目(编号:30871209)

摘　　要：骨腱结合部过度使用性损伤常见于运动员。研究伤后48h进行低强度载荷训练对急性骨腱结合部损伤愈合的影响。研究对象和方法:12只雌性成年新西兰大白兔的后肢通过针刺建立急性损伤组(AI,n=6),伤后48h开始进行四周低强度训练建立伤后低强度训练组(PIERT,n=6)和对照组(CON,n=6)。第四周取样的标本结果提示,PIERT组的骨小梁厚度明显小于AI和CON组;和CON组相比,AI和PIERT组的胶原排列明显紊乱,瘢痕组织多,细胞密度低;PIERT组的纤维软骨带厚度明显厚于AI组。建立了一个定量、可重复骨腱结合部微细损伤动物模型,并发现伤后48h开始低强度训练没有延缓损伤愈合,并对结构重建具有一定促进作用。Bone-tendon junction（BTJ） overuse injuries are common athletic problems.We studies the effects of acute injury on the healing process by low intensity training after resuming training within 48 hours post-injury,as is often the case for athletes.Twelve mature female rabbits were assigned into one of the following groups：acute injury（AI,n=6）,post-injury early return to training（PIERT,n=6） and normal control（CON,n=6）.Tissue specimens were harvested at the fourth week.The trabecular thickness of the PIERT animals was significantly less than those of the AI and CON groups.A histological evaluation revealed poor collagen fibre alignment,extensive scar tissue and lowered cell density in the AI and PIERT groups compared with the CON group,but no significant differences were observed between the AI group and the PIERT group.The fibrocartilage zone thickness in the PIERT group was significantly different from those in AI group.No differences were observed in the Total VOI volume（TV）,Object volume（OBV）,Percent object volume（BV/TV） and trabecular number（Tb.N） among the AI,PIERT and CON groups.In conclusion,a repeatable animal model of bone-tendon junction acute micro-damage by puncture was established.Resuming training in 48 hours did not significantly deteriorate the BTJ injury,and improved bone and fibrocartilage zone remodelling.

关 键 词：骨腱结合部 髌骨 早期伤后训练 定量载荷 损伤愈合 

分 类 号：G804.23[文化科学—运动人体科学]