非离子性糖脂质囊泡的稳定性研究(英文)  

Studies on the Stabilization of Nonionic Glycolipid Vesicles

作　　者：郑立强[1] 沈强[1] 徐桂英[1] 李干佐[1] 

机构地区：[1]山东大学胶体与界面化学教育部重点实验室,山东济南250100

出　　处：《日用化学品科学》2000年第S2期1-6,11,共7页Detergent & Cosmetics

基　　金：ThisworkwaspartlygrantedbyNSFC!(No29973023);KeyProjectsforScience&TechnologyFoundationofEducationMinistry!(No 99183) .

摘　　要：通过对非离子性脂质囊泡的Zeta电位的测定 ,发现在pH =1 6～ 13范围内 ,糖脂质囊泡的表面是带负电荷的。囊泡表面带负电荷的原因有两个 :一是吸附溶液中的OH-离子 ;另一个是在高pH区域 ,糖脂质分子中的糖环上的OH基团的解离。WT5”BZ]:The nonionic synthetic glycolipid ( Mal 3(Phyt) 2), 1,3-di-O-phytanyl-2-O-(β-D-maltotriosyl) glycerol can form unilamellar vesicles in aqueous solutions, and the electrophoretic mobility measurements revealed that the glycolipid vesicles were negatively charged in the pH range between 1 6 and 13. The changes in ζ-potentials as functions of pH and NaCl concentration could be well described by the Gouy-Chapman expression of the surface charges with an assumption that the interfacial charges arise from the “adsorption” of OH - at the vesicle - water interface and the dissociation of hydroxyl groups of the sugar headgroup in a higher pH regime (pH>10), thus the double layer repulsive forces appear a major factor in stabilizing the glycolipid vesicle suspensions.

关 键 词：ζ-电位 囊泡 糖脂质 稳定性 

分 类 号：O646[理学—物理化学]