离子对色谱法测定Roxarsone的含量  

Ion-pair Chromatography for the Determination of Roxarsone

作　　者：陈天文[1] 欧阳瑞珍[1] 张在整[1] 

机构地区：[1]福州大学,福州350002

出　　处：《福建分析测试》2000年第1期1178-1181,共4页Fujian Analysis & Testing

摘　　要：本文提出一种用于测定对氨基苯胂酸硝化反应产物中4-羟基-3-硝基苯胂酸(Roxarsone)及对氨基苯胂酸含量的离子对色谱法,选择甲醇:水=25:75(v/v)作为流动相,0.005mol/L的四丁基氢氧化铵为离子对试剂,用磷酸调至pH=4.0,定量测定重现性良好,对Roxarsone中的杂质对氨基苯胂酸(ASA)的最低检出浓度为0.05μg/mL,结果令人满意。This paper proposes a method for the determination of 4-hydroxy-3-nitro-benzenearsonic acid and arsanilic acid in the nitration reaction product of arsanilic acid by ion-pair chromatography. The mobile phase is water-methanol (75: 25, V/V), using tetrabutylammonium hydroxide as the ion-pair reagent, adjusting its pH to 4. 0 with phosphate acid. The minimum detectable concentration of arsanilic acid is 0. 05μg/mL, it has good reproducibility and good results were obtained.

关 键 词：离子对色谱法 4-羟基-3-硝基苯胂酸 对氨基苯胂酸 

分 类 号：O657.7[理学—分析化学]