Separation of chiral phosphorus compounds on the substituted P-cyclodextrin stationary phase in normal-phase liquid chromatog-raphy  

作　　者：陈慧 吕宪禹 高如瑜 周嘉 王琴孙 

机构地区：[1]National Laboratory of Elemento-Organic Chemistry, Nankai University, Tianjin 300071, China

出　　处：《Chinese Journal of Chemistry》2000年第4期533-536,共4页中国化学（英文版）

基　　金：Project supported by the Fundation of National Laboratory of Elemento-Organic Chemistry, Nankai University.

摘　　要： The separation of enantiomers of a series of eighteen novel nitrogen mustard linked phosphoryl diamide derivatives was investigated on the prepared phenyl carbamate derivative β-cy-clodextrin bonded phase in normal-phase HPLC. Some of the enantiomers could be separated in baseline. The chiral recognition mechanism was also suggested for the separation of chiral phosphorus organic compounds.<正> The separation of enantiomers of a series of eighteen novel nitrogen mustard linked phosphoryl diamide derivatives was investigated on the prepared phenyl carbamate derivative β-cy-clodextrin bonded phase in normal-phase HPLC. Some of the enantiomers could be separated in baseline. The chiral recognition mechanism was also suggested for the separation of chiral phosphorus organic compounds.

关 键 词：Chiral stationary phase nitrogen mustard linked phosphoryl diamide derivatives normal-phase LC Β-CYCLODEXTRIN 

分 类 号：O627[理学—有机化学]