1-Ethyl-2-Fluoro Pyridinium Salt: A Highly Efficient Coupling Reagents for Sterically Hindered Peptide Synthesis  

作　　者：Peng LI Jie Cheng XU (Shanghai Instilute of Organic Chemistry, Chinese Academy of Sciences. Shanghai 200032) 

出　　处：《Chinese Chemical Letters》2000年第5期377-380,共4页中国化学快报（英文版）

基　　金：This work was financially supported by the National Natural Science Foundation of China!(9772045 )

摘　　要：1-Ethyl-2-fluoropyridinium tetrafluoroborate (FEP) was shown to be a very efficient coupling reagent for the synthesis of the hindered peptide with fast reaction speed, low racemization and good yields.1-Ethyl-2-fluoropyridinium tetrafluoroborate (FEP) was shown to be a very efficient coupling reagent for the synthesis of the hindered peptide with fast reaction speed, low racemization and good yields.

关 键 词：FEP peptide RACEMIZATION REACTIVITY 

分 类 号：O626[理学—有机化学]