老年人急性胆管炎CA19—9升高的临床意义  

Clinical significance of elevated CA19-9 level in acute cholangitis in the aged

作　　者：张辉[1] 汪恭恕[1] 余昌俊[1] 朱存如 陈伟[1] 汪正广[1] 

机构地区：[1]安徽医科大学附院干部外科,230022

出　　处：《中国临床保健杂志》1999年第2期88-89,共2页Chinese Journal of Clinical Healthcare

摘　　要：目的 探讨老年人急性胆管炎CA19-9升高的临床意义。方法 放免法检测45例老年人胆道良性疾病病人血清CA19-9水平,将其分为三组:(1)慢性胆囊炎胆囊结石18例;(2)急性胆囊炎13例;(3)急性胆管炎14例。结果 12例急性胆管炎病人CA19-9有不同程度升高(85.7％),正常值为低于30ku/L,最高值达500ku/L;而急性胆囊炎病人中仅1例升高(7.7％),慢性胆囊炎胆囊结石病人中无1例升高。结论CA19-9本身并不完全是肿瘤标志物。老年人急性胆管炎也可致血清CA19-9升高,随着病情的好转其值降为正常。临床上发现老年病人血清CA19-9升高时,应先排除急性胆管炎所致。Objective To evaluate Clinvcal significance of elevated CA19 - 91evel in acute cholangitis in the aged Metheds Serum CA9- 9 was measured by RIA,Included in the study were 45 aged patiendts with benign biliary tract disease who were diveded into three groups: ( l)calculous chronic cholecystitis (N=18);(2)acute cholecystitis (N=14);( 3)acute cholangitis (N=14) ,result 12 of fourteen patients with acute cholangitis had varied elevations of serum CA9-9( 85. 7%) using 30KU/Las a cutoff ,with the maxmum 500KU/L,, Whereas only 1 of thireteen patients with acute cholecystis had elevated CA19-9(7. 7%) , none of patients with calculous chronic cholecystitis had CA19- 9 elevation Con-clusion CA19- 9 itself is not absolutely a tumor marker Acute cholangitis in aged patients can cause elevated CA19- 9 level, which returns to normal after the disease is appropriately treated Once serum cal9-9 isfound elevated in aged patients, acute cholangitis should be excluded firstly

关 键 词：急性胆管炎 CA19-9肿瘤标志物 

分 类 号：R657.4[医药卫生—外科学]