冠状动脉支架术术后再狭窄与临床因素的关系  

Multivariate analysis of clinical factory in restenosis after coronary stenting

作　　者：温尚煜[1] 毛节明[1] 郭丽君[1] 赵一鸣[1] 张福春[1] 牛杰 郭静萱[1] 陈明哲[1] 

机构地区：[1]北京医科大学第三临床医院心内科,北京市100083

出　　处：《岭南心血管病杂志》1998年第2期71-73,共3页South China Journal of Cardiovascular Diseases

摘　　要：目的通过对再狭窄和临床易患因素关系的分析希望找出再狭窄的独立预测因素。方法本研究回顾性分析了60例（共67支血管）在我院成功进行了冠状动脉内支架术，并于术后6个月有完整冠状动脉造影随访资料的病人，通过单因素及多因素方法分析再狭窄与临床因素的关系。结果总再狭窄率为31．3％（21／67）。单因素分析中发现冠状动脉内支架≥3．5mm组的再狭窄率较低，和再狭窄的关系有显著统计学意义（P＜0．01）。术前吸烟、有到病变远端侧支循环、最大球囊充气压和术后最小管腔开放直径较小组的再狭窄率较高，以上4因素和再狭窄的关系有统计学意义（P＜0．05）。多元Logistic回归分析结果显示应用直径≥3．5mm冠状动脉内支架可降低再狭窄率，最大球囊充气压较大和吸烟可使再狭窄率增高。结论冠状动脉内支架直径大小、球囊最大充气压和吸烟为再狭窄的独立预测因素。Objective To found the independent predictors for restenosis after coronary steming.Methods Quantitative angiography was performedon 60 patients (67 successfuly dilated lesions) atangioplasty and at 6- month follow - up, and thenUnivariate and multivariate logistic regression analysis were done to identify correlations of restenosiswith clinical factors. Results The total restenosisrate was 31 .3% (21 of 67 lesions), and accordingto univariate analysis the patients who underwentcoronary tenting ≥ 3.5mm had a lower rate of restenosis (P < 0.01 ). Collateral circulation to the obstruction set, high maximal inflation pressure,smoking and the less minimal lumen diameter afterPTCA made the rate of restenosis highter (P <0.05 ). Multivariate logistic regression analysisshowed that Coronary steming ≥ 3 .5mm had a lowrate of restenosis, but high maximal inflation pres sure and smoking made the rate higher. ConclusionCoronary stent size, maximal inflation pressureand smoking were independent predictors forrestenosis.[

关 键 词：冠状动脉 成形术 临床因素 再狭窄 支架 

分 类 号：R654.2[医药卫生—外科学]