近年病原微生物实验室获得性感染病例分析及其控制策略的初步研究  

Preliminary studies on pathogenic microorganisms laboratory-acquired infections cases in recent years and its control strategies

作　　者：魏强[1] 李晓燕[1] 王雷[1] 卢选成[1] 盖孟楠[1] 武桂珍[1] 侯培森[1] 

机构地区：[1]中国疾病预防控制中心,北京102206

出　　处：《中华实验和临床病毒学杂志》2011年第5期390-392,共3页Chinese Journal of Experimental and Clinical Virology

基　　金：基金项目：国家高技术研究发展计划资助项目（2006AA0224F1）;艾滋病和病毒性肝炎等重大传染病防治专项（2009ZX10004-502）资助

摘　　要：目的分析研究2000--2009年文献报道的引起全球病原微生物实验室获得性感染病例的病原微生物种类、感染途径、发生原因并初步探讨病原微生物实验室获得性感染预防控制策略。方法选择PubMed、Embase、Biosis以及涵盖SCIE、SSCI、CPCI-S和CPCI—SSH的WebofScience作为数据源，以Laboratory—acquired（associated）infections为检索词，检索2000—2009年发表的有关实验室获得性感染文献后，对获取信息和数据进行整理、分析、研究。结果近10年来引起实验室获得性感染病例的病原微生物有19种，其中细菌15种，占78．9％；病毒4种，占21．1％。报道病例83例，其中细菌性病例60例，占72．3％；病毒性病例23例，占27．7％。感染途径以摄人和吸人性感染为主，分别占32．5％和31．3％，感染主要原因为意外事故，占47．O％。结论近年来，病原微生物实验室获得性感染病例仍时有发生，感染的主要原因为意外事故，暴露出实验室工作人员安全意识和规范操作方面的缺陷。实验室工作人员注重安全意识，遵守安全操作规程，仍是预防控制实验室获得性感染发生的关键。Objective To analyze and study types, infections routes and causes of global pathogenic microorganisms laboratory-acquired infections cases reported in the literatures from 2000 to 2009 and to discuss prevention and control strategies. Methods （1）Pathological observation of hepatic specimens： hepatic tissue pathogenic microorganisms laboratory-acquired infections. Methods PubMed, Embase, Biosis and Webs of Science covering SCIE, SSCI, CPCI-S and CPCI-SSH are chosen as data sources, ＂laboratory- acquired （associated） infections＂ are searched as the key words to search laboratory-acquired infections literature published from 2000 to 2009, from which information and data are accessed to be collected, analyzed and researched. Results There are 19 species of pathogenic microorganisms causing laboratory- acquired infections in the last 10 years, including 15 species of bacteria, accounting for 78.9% ; 4 species of virus, accounting for 21.1%. There are 83 cases reported, of which there are 60 bacterial cases, accounting for 72.3% ; and 23 virus cases, accounting for 27.7%. Ingestion and inhalation are main routes of infections, respectively accounting for 32.5% and 31.3% , which are mainly due to accidents, accounting for 47.0%. Conclusion In recent years, pathogenic microbiology laboratory-acquired infections continue to occur, and it is mainly due to accidental infections, which expose laboratory workers＇ low sense of safety and deficient operation methods. Laboratory staff should strengthen their senses of safety and comply with safe operation procedures, which are still the key to prevent laboratory-acquired infections.

关 键 词：实验室感染 感染控制 

分 类 号：R197.2[医药卫生—卫生事业管理]