骨髓活检对急性白血病20例疗效评价  

Assessment of Therapeutic Significance of Bone Marrow Biopsy in Acute Leukemias

作　　者：潘志远 

机构地区：[1]广西梧州市人民医院血液内科

出　　处：《华夏医学》1998年第6期18-20,共3页Acta Medicinae Sinica

摘　　要：对２０例急性白血病患者（包括１例慢粒急粒变）的４８例次骨髓活检标本进行观察，发现１８例完全缓解患者１１例骨髓活检有残存幼稚细胞。提示对这些患者必须继续定期化疗；化疗后间质也产生不同程度的改变，且缓解率明显高于间质无改变患者（Ｐ＜０．０５）；骨髓活检和涂片中细胞增生程度基本一致；Bone marrow biopsies(48 times)were carried out in 20 acute leukemia patients.Residual leukemic cells In 11 of the 18 cases with complete remission,were still detectable histopathologically.In cases with residual leukemic cells,the duration of clinical remission was much shorter,suggested that chemotherapy should by no means be discontinued in such a situation.In cases of complete remission,the interstitial tissue between the marrow cells was found to have undergone degenerative changes,too.And the remission rate in cases showing degenerative changes appeared much longer than those without such changes.The degrees of proliferation of the leukemic cells were essntially the same in the bone marrow biopsy and the smear.Strictural fat reappeared in the interstitial tissue in 13 of the 18 cases with complete remission after chemotherapy.

关 键 词：骨髓活检 缓解 白血病细胞 间质 

分 类 号：R557[医药卫生—血液循环系统疾病]