经皮注射酒精治疗毒性弥漫性甲状腺肿的初步研究  

Preliminary Study on the Treatment for Toxic Diffuse Goiter With Percutaneous Ethanol Injection

作　　者：彭鹰[1] 唐灵[1] 于健[1] 梁志清[1] 

机构地区：[1]广西桂林医学院附属医院内分泌科

出　　处：《华夏医学》1998年第1期39-41,共3页Acta Medicinae Sinica

摘　　要：对２０例毒性弥漫性甲状腺肿患者，在给予口服抗甲亢药短期治疗同时，分３～６次将总量为肿大甲状腺体积６０％的无水酒精浸润性注入甲状腺两侧叶内，与２０例单独口服抗甲亢药治疗患者比较。注射组甲状腺肿平均缩小３１％，Ｐ＜０．０１，有高度显著性意义，对照组缩小仅１６％，Ｐ＞０．０５，无显著性意义，停药后１年内注射组完全缓解率７５％，优于对照组的５５％完全缓解率。未见严重不良反应发生。Along with giving antithyroid drugs orally for shortterm treatment for 20 cases of toxic diffuse goiter,dehydrated alcohol with total dosage as 60% of the volume of enlarged goiter was injected infiltratively into the bilateral lobi of goiter,and compared with another 20 cases who only received antithyroid drugs orally.The goiter decreased 31%in size on average in the ethanol injection group,having significant difference(P<0.01),while that in control group only decreased 16% without significant difference(P>0.05).After drug stopping,the complete remission rate in injection group was 75%,it was superior to that in the control group(that was 55%),and no severe adverse reactions were observed.

关 键 词：经皮注射酒精 毒性弥漫性甲状腺肿 

分 类 号：R581.3[医药卫生—内分泌]