A New Pregnane Glycoside from Dioscorea collettii var. hypoglauca  

作　　者：Hu, K Dong, AJ Kobayashi, H Iwasaki, S Yao, XS 

机构地区：[1]Shenyang Pharmaceut Univ, Dept Nat Prod Chem, Shenyang 110015, Peoples R China [2]NE Pharmaceut Co, Inst Drug Res & Dev, Shenyang 110026, Peoples R China [3]Univ Tokyo, Inst Mol & Cellular Biosci, Tokyo 113, Japan

出　　处：《Chinese Chemical Letters》1998年第8期739-742,共4页中国化学快报（英文版）

摘　　要：A new pregnane glycoside hypoglaucin G was isolated from Dioscorea collettii var. hypoglauca by bioactivity-guided fractionation, which showed a moderate activity of inducing morphological deformation of the Pyricularia oryzae mycelia. The structure of hypoglaucin G was established as 16 beta-(4'-methyl-5'-O-beta-D-glucopyranosyl-pentanoyloxy)-pregn-5-en-3 beta-ol-20-one 3-O-alpha-L-rhamnopyranosyl-(1-->2)-[alpha-L-rhamnopyranosyl-(1-->4)-]-beta-D-glucopyranoside by chemical evidence and spectral analysis, especially by 2D-NMR techniques.A new pregnane glycoside hypoglaucin G was isolated from Dioscorea collettii var. hypoglauca by bioactivity-guided fractionation, which showed a moderate activity of inducing morphological deformation of the Pyricularia oryzae mycelia. The structure of hypoglaucin G was established as 16 beta-(4'-methyl-5'-O-beta-D-glucopyranosyl-pentanoyloxy)-pregn-5-en-3 beta-ol-20-one 3-O-alpha-L-rhamnopyranosyl-(1-->2)-[alpha-L-rhamnopyranosyl-(1-->4)-]-beta-D-glucopyranoside by chemical evidence and spectral analysis, especially by 2D-NMR techniques.

关 键 词：hypoglaucin G Dioscorea collettii var. hypoglauca Pyricularia oryzae 

分 类 号：O629[理学—有机化学]