Inclusion Complexation of β-CD with Phenothiazine and N-Alkylphenothiazine Derivatives  

作　　者：Wen Guang LI Xiu Qin RUAN Qing Xiang GUO You Cheng LIU (Institute of Chemical Metallurgy, Chinese Academy of Sciences, Beijing 100080)(National Laboratory of Applied Organic Chemistry, Lanzhou University, Lanzhou 730000)(Department of Chemistry, Univer 

出　　处：《Chinese Chemical Letters》1998年第11期0-0,0-0,共4页中国化学快报（英文版）

摘　　要：Inclusion of Acyclodextrin (ACD) with phenothiazine 1 and Nalkylpheno-thiazine derivatives (alkyl = ethyl 2, isobutyl 3 and isopentyl 4) in aqueous solution was studied by means of UV-vis spectroscopy. The association constant Ka values for the inclusion of β-CD with 1, 2, 3 and 4 were determined to be 188, 214, 129 and 80 L/mol, respectively. It indicates that the stability of the inclusion complexes is dependent on the structure and the volume of the substituents in the guest compounds.Inclusion of Acyclodextrin (ACD) with phenothiazine 1 and Nalkylpheno-thiazine derivatives (alkyl = ethyl 2, isobutyl 3 and isopentyl 4) in aqueous solution was studied by means of UV-vis spectroscopy. The association constant Ka values for the inclusion of β-CD with 1, 2, 3 and 4 were determined to be 188, 214, 129 and 80 L/mol, respectively. It indicates that the stability of the inclusion complexes is dependent on the structure and the volume of the substituents in the guest compounds.

关 键 词：Β-CYCLODEXTRIN inclusion complex phenothiazine derivatives STABILITY 

分 类 号：O626[理学—有机化学]