A practical synthesis of novel hydroxyl-substituted macrocyclic tri-,tetra- and hexa-amines  

作　　者：薛国平 刘勇 吴成泰 

机构地区：[1]Department of Chemistry,Wuhan University,Wuhan,Hubei 430072,China

出　　处：《Chinese Journal of Chemistry》1998年第6期538-541,共4页中国化学（英文版）

基　　金：Project (No. 29502010) supported by the National Natural Science Foundation of China

摘　　要：Macrocyctic tri- and tetra-amines containing a hydroxyl group in the ring have been prepared in moderate yields by a. 1:1 cyclocondensation of 1,3-dichloro-2-propanol with the disodium salt of N-tosylated diethylenetriamine and triethylenetetraamine. In the case of condensation of 1,3-dichoro-2-propanol with the disodium salt of N-tosylated diethylenetriamine, the 2:2 cyclocondensation product, dihydroxyl macrocyclic hexaamine, was also isolated.Macrocyctic tri- and tetra-amines containing a hydroxyl group in the ring have been prepared in moderate yields by a. 1:1 cyclocondensation of 1,3-dichloro-2-propanol with the disodium salt of N-tosylated diethylenetriamine and triethylenetetraamine. In the case of condensation of 1,3-dichoro-2-propanol with the disodium salt of N-tosylated diethylenetriamine, the 2:2 cyclocondensation product, dihydroxyl macrocyclic hexaamine, was also isolated.

关 键 词：macrocyclic polyamine CYCLOCONDENSATION mesocylic diamine 

分 类 号：O621[理学—有机化学]