Total Synthesis of Antitumor constituent Howiinol A  

作　　者：Sun, SY Yu, DQ 

机构地区：[1]CHINESE ACAD MED SCI,INST MAT MED,BEIJING 100050,PEOPLES R CHINA [2]BEIJING UNION MED COLL,BEIJING 100050,PEOPLES R CHINA

出　　处：《Chinese Chemical Letters》1997年第4期293-294,共2页中国化学快报（英文版）

摘　　要：Howiinol A, an active antitumor constituent from the root and stem bark of Goniothamus howii Meer. (Annoaceae) has been synthesized in nine steps from alpha - D - glucoheptonic gamma - lactone with an overall yield of 12.4%. The absolute configuration of natural howiinol A is further confirmed.Howiinol A, an active antitumor constituent from the root and stem bark of Goniothamus howii Meer. (Annoaceae) has been synthesized in nine steps from alpha - D - glucoheptonic gamma - lactone with an overall yield of 12.4%. The absolute configuration of natural howiinol A is further confirmed.

分 类 号：O621[理学—有机化学]