Single Polar Compound Bioelectret Material and Its Influence on the Cell Growth  

单极性复合生物驻极体材料及其对细胞生长的影响(英文)

作　　者：史向阳[1] 邓百明[1] 孙曹民[1] 

机构地区：[1]北京理工大学化工与材料学院

出　　处：《Journal of Beijing Institute of Technology》1997年第4期31-39,共9页北京理工大学学报（英文版）

摘　　要：To explore the influence of compound bioelectret material′s dielectric property on the cell growth,several kinds of compound bioelectret materials of collagen/chitosan were developed Their TSDC(thermally stimulated depolarization current)spectra were analyzed,and the compound bioelectret collagen/chitosan whose t α and I α were 37℃ and 2×10 -9 A respectively at polarized state was selected The cell culture study showed that the compound bioelectret material could promote normal cell growth when singly negatively polarized,and could inhibit cancer cell growth when singly positively polarized It proves that the rational designation of compound bioelectret has a broad application for clinical medicine为了探索复合生物驻极体材料的带电性能对细胞生长的影响，研制了几种不同配比的胶原／壳聚糖复合生物驻极体材料，分析了它们的ＴＳＤＣ图谱（热刺激去极化电流谱），筛选出了一种性能较好的胶原／壳聚糖复合生物驻极体材料，它在极化状态时，主峰温度和电流分别为３７℃和２×１０－９Ａ细胞培养实验研究发现，当该材料负极化时，能够有效地促进正常细胞的生长；当材料正极化时，能够抑制癌细胞的生长这表明，对复合生物驻极体材料进行合理设计。

关 键 词：bioelectret COLLAGEN CHITOSAN TSDC cell culture 

分 类 号：Q64[生物学—生物物理学]