Studies on the energy transfer system of terbium-norfloxacin chelate and its interaction with serum albumins  

作　　者：Xu, Y Shen, HX Huang, HG 

机构地区：[1]NANKAI UNIV,DEPT CHEM,TIANJIN 300071,PEOPLES R CHINA [2]HEBEI INST TECHNOL,DEPT CHEM ENGN,TANGSHAN 063009,HEBEI,PEOPLES R CHINA

出　　处：《Chinese Journal of Chemistry》1997年第2期138-143,共6页中国化学（英文版）

基　　金：Project supported by the National Natural Science Foundation of China.

摘　　要：The energy absorbed by norfloxacin could be transferred to terbium(III) through chelation of norfloxacin with terbium(III), then the characteristic fluorescence emission could be observed. The interaction of serum albumins with norfloxacin have been investigated in this paper. The results showed that HSA could inhibit the energy transfer between norfloxacin and terbium(III). But, BSA could not. It was shown that the binding properties of norfloxacin to HSA and BSA were totally different.The energy absorbed by norfloxacin could be transferred to terbium(III) through chelation of norfloxacin with terbium(III), then the characteristic fluorescence emission could be observed. The interaction of serum albumins with norfloxacin have been investigated in this paper. The results showed that HSA could inhibit the energy transfer between norfloxacin and terbium(III). But, BSA could not. It was shown that the binding properties of norfloxacin to HSA and BSA were totally different.

关 键 词：NORFLOXACIN terbium(III) energy transfer HSA BSA 

分 类 号：O629[理学—有机化学]