用于单个生物分子分析的纳米操作和纳米测量技术  

The technique of nano-manipulation and nano-measurement for single biomolecule analysis

作　　者：余兴龙[1] 王佳[1] 

机构地区：[1]清华大学精密仪器与机械学系

出　　处：《仪器仪表学报》1996年第S1期94-97,共4页Chinese Journal of Scientific Instrument

基　　金：国家自然科学基金

摘　　要：本文叙述了用于单个生物分子分析的纳米操作和纳米测量技术。光镊子能镊住大分子，按照测量要求进行操作。近场光学扫描显微术是结构生物学的重要研究手段，可以测量大分子的结构。分子马达力学特性测量技术的出现是分子马达研究的新突破，能测出单个分子马达的力学参数。This paper describes technique of nano-manipulation and nano-measurement for single biomolecule analysis.A large molecule have been brought using a optical tweezer which can move as measurement requirement. The near-field optical scanning microscope is an important.equipment for construral biology, constructure of large molecule is determined using it.It is new breakthrought in molecular reasearch that measure technique o f single of molecular motor mechanics have been developed. Force and displacement on molecular motor moving are measured in nanometer and piconewton scale.

关 键 词：测量技术 生物分子 光镊子 分子马达 纳米 力学特性 声光调制器 光电倍增管 压电陶瓷驱动器 扫描显微术 

分 类 号：TB4[一般工业技术]