经食管多普勒定量估测冠状动脉血管阻力及血管储备  

Quantitative Assessment of Coronary Vascular Resistance and Vascular Reserve by Transesophageal Doppler Echocardiography

作　　者：赵文强[1] 蔡妙贞[1] 杜微云[1] 曹润萧[1] 李卓仁[1] 郭南山[1] 邢植斐[1] 李广镰[1] 

机构地区：[1]广州市第一人民医院心内科

出　　处：《中国超声医学杂志》1996年第S1期10-12,共3页Chinese Journal of Ultrasound in Medicine

摘　　要：应用经食管多普勒超声心动图（ＴＥＥ）对３０例冠状动脉造影患者测量注射潘生丁前后左前降支平均舒张期血流率（Ｖｃｏｒ）、冠脉血管阻力（Ｒｃｏｒ）和冠脉血管储备（ＣＶＲ）。静息状态正常组与狭窄各组平均动脉压（ＭＡＰ）、Ｖｃｏｒ和Ｒｃｏｒ无显著差异。注射潘生丁后狭窄各组较对照组的Ｒｃｏｒ显著增加、Ｖｃｏｒ和ＣＶＲ显著降低而ＭＡＰ基本不变；ＰＤＳ＜７５％与≥７５％组的注药后Ｒｃｏｒ和ＣＶＲ无显著差异，血管狭窄积分（ＡＳＩ）＜１．５ｃｍ与≥１．５ｃｍ组两指标差异显著。注药后的Ｒｃｏｒ与ＡＳＩ成正相关（ｒ＝０．６３，Ｐ＜０．０１），与ＰＤＳ不相关；ＣＶＲ与ＡＳＩ和ＰＤＳ成较好的负相关（ｒ＝－０．８２，－０．５２）。本研究为冠状动脉病变功能严重度的定量估价提供了参考依据。Transesophageal Doppler echocardiography(TEE)was used to detect mean diastolic flow rate(Vcor),coronary vascular resistance(Rcor)and coronary vascular reserve(CVR)in the left anterior descending9(LAD)coronary artery before and after dipyridamole infusion in 30 patients undergoing coronary angiography.In rest condition mean artery pressure(MAP),Vcor and Rcor in all stenosis groups were unsigniflcantly different from in normal group.But after dipyridamole infusion Rcor were significantly increasing,Vcor and CVR significantly deceasing and MAP basically unchange in all stenosis groups versus in normal group.Rcor after dipyridamole infusion and CVR were unsignificantly different in Grp PDS<75%vs in Grp PDS≥75%but significantly different in Grp angiostenosis integral(ASI)<1.5cm vs in Grp ASI≥1.5cm.Rcor after dipyridamole infusion had positive correlation(r=0.63,P<0.01)with ASI and had no correlation with percentage of diameter stenosis(PDS).CVR had negative correlation with ASI(r=-0.82,p<0.001)and PDS(r=0.52,P<0.05).This study provides a reliable referential basis for quantitative assessment of functional severity of coronary artery lesion.

关 键 词：经食道多普勒超声 冠脉血管阻力 冠脉血管储备 

分 类 号：R445.1[医药卫生—影像医学与核医学]