大鼠大脑皮层－尾壳核和尾壳核－黑质间的往返定位投射  

THE TOPOGRAPHICALLY ORGANIZED RECIPROCAL CONNECTIONS BETWEEN THE CEREBRAL CORTEX AND CAUDATE-PUTAMEN, CAUDATE-PUTAMEN AND SUBSTANTIA NIGRA IN THE RAT

作　　者：李云庆[1] 王智明[1] 施际武[1] 

机构地区：[1]第四军医大学基础部解剖学教研室梁脑研究中心

出　　处：《解剖学报》1996年第3期243-247,共5页Acta Anatomica Sinica

摘　　要：用霍乱毒素Ｂ亚单位（ＣＢ）追踪法系统地研究了大鼠大脑皮层与尾壳核和尾壳核与黑质之间的定位投射。将ＣＢ分别泳入尾壳核不同节段的不同区域后，大脑皮层内的逆标胞体和顺标终末主要见于额叶１区和２区、顶叶１区和２区以及颗粒岛皮质；黑质内的顺标终末主要见于网状带的不同部位，而逆标胞体则主要见于致密带和腹侧被盖区。本研究结果说明在大鼠大脑皮层－尾壳核和尾壳核－黑质之间存在着且有点对点定位特征的往返联系。这种定位投射对躯体运动的精细调节提供了形态学基础。The topographic connection between the cerebral cortex and caudate-putamen caudate-putamen and substantia nigra in the rat were systemically investigated with cholera toxin B subunit(CB) tracing technique, After iontophoretic injections of CB into the medial, intermediate, or lateral region of the caudate-putamen at the rostral,middle,or caudal level,in the cerebral cortex,CB retrogradely labeled neurons and terminals were observed in the area 1 and 2 of the frontal cortex,area 1 and 2 of the parietal, and granular insular cortex, respectively;in the substantia nigra, CB anterogradely labeled terminals were seen in different subregions of the pars reticulata, while CB retrogradely labeled neurons were encountered in the pars compacta;in the ventral termental area,CB retrogradely labeled neurons were also observed.The present results indicated that there were typical point-to-point topographically organized reciprocal connections between cerebral cortex and caudate-putamen. Those topographic projections may provide the morphological bases for the precise control of the somatic movements.

关 键 词：大脑皮层 尾壳核 黑质 定位投射 霍乱毒素B亚单位 大鼠 

分 类 号：R338[医药卫生—人体生理学]