Mobi-C人工颈椎椎间盘治疗颈椎病的早期临床观察  

Early clinical observation on Mobi-C disc prosthesis in treatment of cervical spondylosis

作　　者：祁磊[1] 李牧[1] 侯勇[1] 聂林[1] 

机构地区：[1]山东大学齐鲁医院脊柱外科,山东250012

出　　处：《脊柱外科杂志》2011年第5期298-301,共4页Journal of Spinal Surgery

摘　　要：目的观察应用Mobi-C人工颈椎椎间盘治疗颈椎病的早期临床疗效。方法 2009年5月～2010年6月应用Mobi-C人工颈椎椎间盘治疗35例患者,共进行了45个间隙的人工椎间盘置换。通过颈椎正侧位和过伸、过屈位X线片测量置换节段术前和术后的活动度(range of motion,ROM)和颈椎整体曲度。应用日本骨科学会(JapaneseOrthopaedic Association,JOA)评分和疼痛视觉模拟量表(visual analogue scale,VAS)评分评价术后颈脊髓功能以及颈部和上肢疼痛症状。对数据进行统计学分析。结果所有患者随访12～24个月,平均17.5个月,本组病例置换节段术前ROM为8.6°±2.4°,末次随访时ROM为9.1°±2.1°,与术前相比差异无统计学意义(P>0.05)。颈椎整体曲度术前为11.7°±9.6°,末次随访时为14.5°±7.3°,与术前相比差异有统计学意义(P<0.05)。24例患者术前有颈脊髓受压的表现J,OA评分为9.4±1.4分,末次随访时为15.0±1.1分,与术前相比差异有统计学意义(P<0.05)。26例患者术前有不同程度的颈肩痛和上肢痛,VAS评分为6.7±1.2分,术后为1.3±0.8分,与术前相比差异有统计学意义(P<0.05)。结论应用Mobi-C人工颈椎椎间盘置换术治疗颈椎病近期可以保持置换节段的运动,改善颈椎曲度,并取得良好的临床疗效。Objective To observe the early clinical effect of Mobi-C disc prosthesis in treatment of cervical spondylosis.Methods A total of 35 patients（including 45 levels） undergoing anterior cervical discectomy and cervical total disc replacement with Mobi-C disc prosthesis from May 2009 to June 2010 were enrolled in the study.Range of motion（ROM） of operated segments and C2-7 lordosis angle were measured through neutral and dynamic hyperextension and hyperflexion reontgenographs before and after operation.Cervical spinal cord function and pain of neck and upper extremities were evaluated through Japanese Orthopaedic Association（JOA） and visual analogue scale（VAS） scores.All data were analyzed statistically.Results All patients were followed up for 12-24 months,mean 17.5 months.Operated segmental ROM was 8.6°±2.4° before operation and 9.1°±2.1° at the final follow-up,without statistical significance between them（P〈0.05）.The C2-7 lordosis angle was 11.7°±9.6° preoperatively and 14.5°±7.3° at the final follow-up,with statistical significance between them（P〉0.05）.In the 35 patients,24 had the symptoms of myelopathy to different extent before surgery,with a JOA score of 9.4±1.4,and the score was increased to 15.0±1.1 at the final follow-up（P〈0.05）.And 26 patients suffered from pain of neck and upper extremities,with a VAS score of 6.7±1.2,which was decreased to 1.3±0.8 at the final follow-up（P〈0.05）.Conclusion Artificial cervical disc replacement with Mobi-C disc prosthesis preserves operated segmental ROM,improves cervical lordosis,and produces satisfactory clinical outcomes during the early follow-up.

关 键 词：颈椎 颈椎病 人工关节 关节成形术 置换 活动范围 关节 

分 类 号：R681.531[医药卫生—骨科学]