术后切口感染危险因素的病例对照研究  

Case control study on the risk factors for postoperative wound infection of the surgical pa-tients

作　　者：胡东升[1] 张玉祥[1] 郗园林[1] 张卫东[1] 时松和[1] 

机构地区：[1]河南医科大学,河南油田卫生处

出　　处：《中华医院感染学杂志》1995年第3期129-131,共3页Chinese Journal of Nosocomiology

摘　　要：本研究对某医院１９９２年７月～１９９３年９月期间住院的外科病人术后切口感染及其危险因素进行了前瞻性监测研究，共监测外科住院病人４２９８例，其中１５３例手术病人发生术后切口感染，２６３５例手术病人未发生任何部位的医院感染。应用成组的病例对照研究方法，通过单因素分析，发现切口分类、术前预防应用抗生素、暴露于ＩＣＵ、导尿、动、静脉插管、术中使用呼吸机、手术时间、引流和术后切口感染有显著的联系。Ｌｏｇｉｓｔｉｃ回归分析筛选出了５个互相独立的与术后切口感染有显著联系的因素，它们是术前预防应用抗生素、引流切口分类、手术时间≥２小时、暴露于ＩＣＵ，但术前预防应用抗生素与术后切口、感染呈负相关。The case control study was carried for the postoperative wound infection and its risk factors on the surgical service at a hospital from July 1992 to September 1993 in this paper.4298 surgical pa-tients(include operative and non-operative patients)enrolled in the study, 153 operative patients devel-oped postoperative wound infection,2635 operative patients didn't any nosocomial infection。 The rela-tionship between all risk factors and postoperative wound infection was studied with case control study in group method by means of univariate and multivariate statistical technique, Univariate analysis se-lected the following variables were significantly associated with a high risk for developing postoperative wound infection: wound classification antibiotic prophylaxis before operation,exposed to ICU, urinary catheter, artery or/and vein catheter, using respiratory machine during operation,and drain used By Logistic regression analysis,five variables were identified that were independent of each other and highly predictive for subsequent postoperative wound infection。 They were antibiotic prophylaxis before opera-tion,drain used, wound classication, length of operation≥2 hours,exposed to ICU,but antibiotic prophylaxis was negatively associated with postoperative wound infection。

关 键 词：术后切口感染 危险因素 多因素分析 

分 类 号：R619.3[医药卫生—外科学]