复脉抗衰注射液对实验性冠状动脉痉挛家兔TXB_2、6-K-PGF_(1α)的影响  

Effect of TCM-WM Treatment on TXB_2 and 6-k-PGF1α of Coronary Artery Spasm in Rabbits

作　　者：李树仁[1] 王士昌[1] 肖文良[1] 孙述强[1] 

机构地区：[1]河北医学院附属第三医院

出　　处：《中国中西医结合杂志》1995年第S1期36-37,367,共3页Chinese Journal of Integrated Traditional and Western Medicine

摘　　要：本研究观察了中药复脉抗衰注射液、硝酸甘油及二者合用对实验性冠状动脉痉挛家兔血中血栓素 B_2(TXB_2)、6-酮-前列腺素 F_(1α)(6-K-PGF_(1α))的影响。结果显示:中西药合用组 TXB_2升高、6-K-PGF_(1α)降低的幅度均较复脉抗衰液组、硝酸甘油组小(P 均<0.05),说明二药合用作用增强。The rabbit model of coronary artery spasm was made by means of intravenous injecting pituitrin.The changes of electrocardiagram and TXB_2,6-k-PGF_(1α)were observed before and after treatment of Fumai Kangshuai (复脉抗衰)injection,nitroglycerin and both of them.The results showed that the myocardial ischemia and the changes of TXB_2 elevation and 6-k-PGF_(1α)reduction in TCM-WM group were better than those in the both groups of TCM and WM alone.But it has no statistical difference between the last two groups.

关 键 词：冠状动脉痉挛 血栓素 B₂ 6-酮-前列腺素 F₁α 复脉抗衰注射液 硝酸甘油 

分 类 号：R285.5[医药卫生—中药学]