Synthesis of 1,4,6-tri-O-benzyl myo-inositol-A key intermediate to myo-inositol-1,2,5-O-trisphosphate  

作　　者：YUAN, Cheng-Ye ZHAI, Hai-Xiao WENG, Guan-HongShanghai Institute of Organic Chemistry, Chinese Academy of Sciences, Shanghai 200032, China 

出　　处：《Chinese Journal of Chemistry》1994年第2期174-178,共5页中国化学（英文版）

基　　金：Project supported by the National Natural Science Foundation of China。

摘　　要： A new synthetic approach to 1,4,6-tri-O-benzyl myo-inositol was described on the basis of the regioselective benzylation of 1,2-O-isopropylidene-4,6-di-O-benzyl myo-inositol, subsequent acid hydrolysis, phosphorylation with tetrabenazylpyrophosphate and appropriate deprotec-tion.A new synthetic approach to 1,4,6-tri-O-benzyl myo-inositol was described on the basis of the regioselective benzylation of 1,2-O-isopropylidene-4,6-di-O-benzyl myo-inositol, subsequent acid hydrolysis, phosphorylation with tetrabenazylpyrophosphate and appropriate deprotec-tion.

关 键 词：MYO-INOSITOL synthesis regioselective benzylation. 

分 类 号：O621[理学—有机化学]