THE EFFECT OF ACUPUNCTURE ON PREVENTION AND TREATMENT OF ISCHEMIC ARRHYTHMIA AND THE RELATION BETWEEN EFFECT OF ACUPUNCTURE AND CHOLINERGIC MUSCARINE-LIKE RECEPTORS  

作　　者：Guan Xinmin Zhang Jian Shi Bo Ouyang Xingbiao 

机构地区：[1]Research Department of Acupuncture Anesthesia Mechanism&Department of Neurobiology,Tongji Medical University,Wuhan 430030,China [2]Department of Physiology,Jinzhou School of Health,Jinzhou,Liaoning Province,China

出　　处：《World Journal of Acupuncture-Moxibustion》1993年第1期39-42,48,共5页世界针灸杂志(英文版)

基　　金：This project was supported by the National Natural Science Foundation of China, 3870563.

摘　　要：For investigating the effect of acupuncture on ischemic arrhythmia and its mech-anism, adult albino rats with ligated anterior descending branch of coronary artery as experimentalmodel were treated with or without acupuncture, and others with imitative operation but without bothcoronary artery ligation and acupuncture treatment were used as control. It was found in acupuncturegroup that the fibrillation-liability of ischemic myocardium was efficiently decreased, the affinity ofAch-M receptors on membranes of ischemic myocardium was markedly increased, and the tolerance ofischemic myocardium to atropine was elevated in the experiment of atropine inducing fibrillation.These results indicate that acupuncture may play a therapeutic role on ischemic arrhythmia throughactivating the activity of muscarine-like receptors of cholinergic nervous system.For investigating the effect of acupuncture on ischemic arrhythmia and its mech- anism, adult albino rats with ligated anterior descending branch of coronary artery as experimental model were treated with or without acupuncture, and others with imitative operation but without both coronary artery ligation and acupuncture treatment were used as control. It was found in acupuncture group that the fibrillation-liability of ischemic myocardium was efficiently decreased, the affinity of Ach-M receptors on membranes of ischemic myocardium was markedly increased, and the tolerance of ischemic myocardium to atropine was elevated in the experiment of atropine inducing fibrillation. These results indicate that acupuncture may play a therapeutic role on ischemic arrhythmia through activating the activity of muscarine-like receptors of cholinergic nervous system.

关 键 词：Acupuncture treatment ARRHYTHMIA Myocardial infarction Cholinergic nerve M receptor 

分 类 号：R245[医药卫生—针灸推拿学]