Higher Order Cuprate Species( Ⅱ )——Stereospecific Carbocupration of Terminal Alkynes and Its Synthetic Utility for ( ± )-Ipsenol and (E)-β-Farnesene  

作　　者：PAN Yi-jun , XU Zhang-huang, CHEN Jia-wei SUN Dong-chen (Department of Chemistry, Hubei University, Wuhan, 430062) To whom correspondence should be addressed. 

出　　处：《Chemical Research in Chinese Universities》1993年第2期104-109,共6页高等学校化学研究（英文版）

基　　金：Supported by the National Natural Science Foundation of China

摘　　要：The stereospecific carbocupration of terminal alkynes via higher order cuprates to give 1,1'-disubstituted olefins with 99% configuration purity is described. Its synthetic utility as a general method for the preparation of substituted olefins is further illustrated by the direct synthesis of (±)-ipsenol and (E)-β-farnesene with highly geometric purity of the carbon-carbon double bond.The stereospecific carbocupration of terminal alkynes via higher order cuprates to give 1,1'-disubstituted olefins with 99% configuration purity is described. Its synthetic utility as a general method for the preparation of substituted olefins is further illustrated by the direct synthesis of (±)-ipsenol and (E)-β-farnesene with highly geometric purity of the carbon-carbon double bond.

关 键 词：Higher order cuprate Terminal alkyne Carbocupration STEREOSPECIFIC 

分 类 号：O6[理学—化学]