A novel regio-and stereo-specific hydrohalogenation reaction of 2-alkynoic acids and their derivatives  

作　　者：LU,Xi-Yan ZHU,Guo-Xin MA,Sheng-Ming Shanghai Institute of Organic Chemistry,Chinese Academy of Sciences,Shanghai 200032 

出　　处：《Chinese Journal of Chemistry》1993年第3期267-271,共8页中国化学（英文版）

基　　金：Project supported by the National Natural Science Foundation of China and Chinese Academy of Sciences.

摘　　要：The nucleophilic hydrohalogenation of 2-alkynoic acids anti their derivatives by heating with lithium halides iu HOAc afforded the thermodynamically unfavorable 3-halo-2 (Z)- alkenoic acids and their derivatives stereospecificallyThe nucleophilic hydrohalogenation of 2-alkynoic acids anti their derivatives by heating with lithium halides iu HOAc afforded the thermodynamically unfavorable 3-halo-2 (Z)- alkenoic acids and their derivatives stereospecifically

关 键 词：A novel regio-and stereo-specific hydrohalogenation reaction of 2-alkynoic acids and their derivatives 

分 类 号：O6[理学—化学]