扩张型心肌病血液流变性变化及机理探讨  

HEMORHEOLOGICAL CHANGES IN DILATED CARDIOMYOPATHY AND THEIR POSSIBLE MECHANISMS

作　　者：张周良[1] 刘淮阳[1] 刘茂贤[1] 邓明亮[1] 

机构地区：[1]第四军医大学唐都医院检验科,陕西西安710032

出　　处：《中国血液流变学杂志》1993年第3期16-18,共3页Chinese Journal of Hemorheology

摘　　要：作者观察了２０例扩张型心肌病（ＤＣＭ）血液流变学１２项指标及血栓素（ＴＸＢ２），前列腺环素（６－酮－ＰＧＦ１α）。当现ＤＣＭ较正常人全血高切、低切粘度，全血高切、低切还原粘度，血浆粘度，纤维蛋白原，Ｔ／６比值等指标升高（ｐ＜０．０５或ｐ＜０．０１）；结果显示，ＤＣＭ存在着血液高粘滞，其主要原因是红细胞聚集性升高，红细胞变形能力下降．We have studied the changes in 12 hemorheological Variables and periphereal Plasma TXB2, 6-Keto-PGF1α. in 20 cases of cardiomyopathy, and found an increase in whole blood viscosity (in high shear and low shear), reducing blood viscosity (in high shear and low shear), plasma viscosity, fibriogen and T/6 ratio (p<0.05 or p<0. 01), when camparing with the normal group. The data suggest: there is hyperviscosity in DCM due to increased erythrocyte aggregation and weakened erythrocyte deformability.

关 键 词：扩心病 血液流变 血栓素 前列环素 

分 类 号：R4[医药卫生—临床医学]