Enhancing Effect of Monosialoganglioside GM1 on Learning and Memory in Aged Rats  

作　　者：郑金泽 梅镇彤 

机构地区：[1]Shanghai Brain Research Institute, Academia Sinica, Shanghai 200031, PRC [2]Shanghai Institute of Physiology, Academia Sinica, Shanghai 200031, PRC

出　　处：《Chinese Science Bulletin》1993年第13期1139-1142,共4页

摘　　要：Introduction Gangliosides are found at high concentration in CNS, and are essentially combined with neuronal membrane. The chemical structures of gangliosides have been determined. They are a family of molecules consisting of a lipid portion anchored in the plasma membrane and a carbohydrate portion on the outer cell surface containing one or more sialic acid residues. The hydrophihc carbohydrate portion is related to the regulation of Ca²⁺ channel. Exogenous ganglioside administration may have facilitatory effects on

关 键 词：MONOSIALOGANGLIOSIDE GM1 DISCRIMINATION learning memory RETENTION aged rat. 

分 类 号：N[自然科学总论]