不同海拔高度喂饲胆固醇家兔血脂改变的对照研究  

CONTROL-STUDY ON BLOOD-LIPID CHANGES OF RABBITS FED CHOLESTEROL AT DIFFERENT ALTITUDES

作　　者：张鑫生[1] 宋国忠[1] 齐文斌[1] 张玲荣[1] 张秀芳[1] 魏国庆[1] 

机构地区：[1]青海省人民医院老年病研究室

出　　处：《高原医学杂志》1993年第2期36-39,共4页Journal of High Altitude Medicine

摘　　要：本文对比观察了不同海拔高度喂饲胆固醇家兔血脂的改变,结果表明:①喂饲高胆固醇食物后,不同海拔高度的甲、乙两组家兔血浆中胆固醇(TC)、低密度脂蛋白胆固醇(LDL—C)、甘油三脂(TG)均明显升高(P<0.01),而高密度脂蛋白胆固醇(HDL—C)升高的幅度较小。②海拔愈高,血脂中致动脉粥样硬化(AS)成份TC、LDL—C升高的幅度愈小,而抗AS成份HDL—C升高幅度较大,这些改变可能是高原地区AS和冠心病(CHD)低发的重要原因之一。Blood—lipid changes of the rabbits fed cholesterol at different altitudes were studied comparatively in this paper. The results showedl. TC, LDL—C and TG in rabbit plasma of A and B groups were inceased significantly (P<0.01) at different altitudes after feeding cholesterol and HDL—C was inceased in the B group (P<0.05); 2. The higher the altitude, the lower the TC and LDL—C promot- ing atherosclerosis (AS) and the higher the HDL—C retarding AS. These changes probably are the one of main factors that the incidence in AS and coronary heart disease (CHD) is low at high altitude.

关 键 词：高原 兔 血脂 动脉粥样硬化 冠心病 

分 类 号：R8[医药卫生—临床医学]