抗生素应用220例临床分析  

Clinical Evaluation of Antibiotic Application of 220 Cases

作　　者：何连德[1] 吕增春[1] 赵云琴[1] 

机构地区：[1]解放军总医院医疗质量管理研究室

出　　处：《中华医院感染学杂志》1993年第1期42-45,共4页Chinese Journal of Nosocomiology

摘　　要：作者报告了1991年5月～8月随机检查出院(包括死亡)病案300份,以探讨抗生素的合理应用。其中220例使用了抗生素12类38种。计应用合理或基本合理的163例(占74.09％),应用不合理的57例(占25.19％),应用不合理表现在七个方面:(1)无明确应用抗生素指征者21例(36.84％);(2)选用抗生素起点过高5例(8.77％);(3)不符合联合用药原则2例(3.51％);(4)术前预防用药时间过长6例(10.53％);(5)氨基糖甙类使用不当者19例(33.33％);(6)频繁更换抗生素2例(3.51％);(7)长期使用广谱抗生素,导致不良反应的2例(3.51％)。本文结合具体病例讨论抗生素合理应用的一些问题,并对应用情况进行了评价。The antibiotic application of 220 patients were studied, We randomly checked 300 cases hospitaled (including death) records, 220 cases of those have been applied with antibiotic of 38 kinds in 12 categories. The results showed 163 cases (74.09%) are reasonable or basically reasonable, but 57 cases (25.91%) unreasonable. The following seven aspects show the unreasonable application of antibitic: (1)There are no definite indication of applying antibiotic in 21 cases (36.84%), (2)Unsuitable use of aminoglycoside in 19 cases (33.33%).(3) Applying medicine over a too long period of time for precaution before operation in 6 cases (10.53%),(4)Applying antibiotic at a too high atarting point in 5 cases (8.77%).(5)Not can form to the principles of jointly used medicines in 2 cases (3.51%),(6)Frequentlty change antibiotic kinds or categeries, 2 cases (3.51%).(7)Use wide-spectrum an- tibiotic over a long period of time and result in adverse reaction, 2 cases(3.51%).

关 键 词：抗生素 合理应用 适应证 副作用 

分 类 号：R197[医药卫生—卫生事业管理]