EFFECTS OF HUMAN BLOOD CONSTITUENTS ON FORMATION OF DNA-CARCINOGEN ADDUCTS AFdG REVEALED BY 32p-POSTLABELLING  

作　　者：沈建华 M.WEGENKE T.WOLFF 

机构地区：[1]Shanghai Institute of Entomology, Academia Siniea, Shanghai 200025, PRC [2]Institut für Toxikologie, Gesellschaft für Strahlen-und Umweltforschung, D-8042 Neuherberg München, FRG

出　　处：《Chinese Science Bulletin》1990年第21期1827-1829,共3页

摘　　要：The formation of DNA-adducts, i.e. the covalent modification of DNA molecules with carcinogens, is the initial event in carcinogenesis. In the organisms, most of the genotoxic chemicals must be first converted into electrophilic metabolites, and then covalently hind with the nucleophilic sites of DNA molecules to form DNA-adducts.

关 键 词：DNA-adducts 32p-postlabelling 2-aminofluorene(2-AF) human blood. 

分 类 号：N[自然科学总论]