CORRECTION OF DNA REPAIR GENE DEFICIENCY IN MAMMALIAN CELLS BY HUMAN HeLa S3. DNA TRANSFECTION  

CORRECTION OF DNA REPAIR GENE DEFICIENCY IN MAMMALIAN CELLS BY HUMAN HeLa S3. DNA TRANSFECTION

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作  者:章扬培 夏寿萱 白晓彬 范国才 

机构地区:[1]Institute of Radiation Medicine, Academy of Military Medical Sciences, Beijing 100850,PRC

出  处:《Chinese Science Bulletin》1990年第3期250-255,共6页

基  金:Project supported by the National Natural Science Foundation of China

摘  要:Study on the DNA damage and repair, especially in the mammalian cells, is one of the frontier topics in life sciences. By means of human DNA-mediated gene transfer (DMGT) method, the genes responsible for DNA repair are introduced into two kinds of repair gene defective mammalian cells. The purpose is to correct their gene deficiency and to study the mechanism of DNA damage and repair induced by radiation or alkylating agents.

关 键 词:DNA repair GENE GENE DEFECTIVE cell GENE transfer. 

分 类 号:N[自然科学总论]

 

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