Assignment of the non-exchangeable proton resonances and conformational analysis of oligonucleotide DNA d(TTGGGGTT)by twodimensional nuclear magnetic resonance methods  

作　　者：DONG,Yan-Hong TANG,Wen-Xia DAI,An-Bang Coordination Chemistry Institute,Nanjing University,Nanjing 210008WU,Jia-Zhen Beijing Biophysics Institute,Academia Sinica,Beijing 100080van BOOM,J.H. REEDIJK,J. STRUIK,A.F. Department of Chemistry,Gorlaeus Laboratories,Leiden University,Leiden,The Netherlands 

出　　处：《Chinese Journal of Chemistry》1990年第3期246-250,共0页中国化学（英文版）

摘　　要：Two-dimensional NMR study on the single-stranded octadeoxynucleotide,d(TT- GGGGTT)is presented.Assignments of the base protons,the H1′,H2′ and H2″ protons were made by two-dimensional Nuclear Overhauser Enhancement Spectroscopy(NOESY)and two-dimensional homonuclear J-correlated Spectroscopy(COSY).The result indicates that the overall structure of the single-stranded d(TTGGGGTT)is a right-handed B-type helix.Two-dimensional NMR study on the single-stranded octadeoxynucleotide,d(TT- GGGGTT)is presented.Assignments of the base protons,the H1′,H2′ and H2″ protons were made by two-dimensional Nuclear Overhauser Enhancement Spectroscopy(NOESY)and two-dimensional homonuclear J-correlated Spectroscopy(COSY).The result indicates that the overall structure of the single-stranded d(TTGGGGTT)is a right-handed B-type helix.

关 键 词：Assignment of the non-exchangeable proton resonances and conformational analysis of oligonucleotide DNA d DNA 

分 类 号：O6[理学—化学]