PREVOST-WOODWARD HYDROXYLATION OF 3,5-CYCLO-24S-ETHYL-CHOLEST-22-EN-6-ONE  

作　　者：Institute of Organic Chemistry,Lanzhou University,Lanzhou 730000Xiao Tian LIANG Institute of Materia Medica,Nan-wei Road,Beijing 100050 

出　　处：《Chinese Chemical Letters》1990年第1期25-26,共2页中国化学快报（英文版）

摘　　要：Preost-Woodward hydroxylation of 2 gave the 22S,23S-glycol(3), contrary to expectation.It is suggested that the formation of the two possible iodonium ions(4a and 4b)are reversible,thus allowing the discriminatory acetoxy group to follow the less hindered route,reacting with 4a virtually exclusively.Preost-Woodward hydroxylation of 2 gave the 22S,23S-glycol(3), contrary to expectation.It is suggested that the formation of the two possible iodonium ions(4a and 4b)are reversible,thus allowing the discriminatory acetoxy group to follow the less hindered route,reacting with 4a virtually exclusively.

关 键 词：PREVOST-WOODWARD HYDROXYLATION OF 3 5-CYCLO-24S-ETHYL-CHOLEST-22-EN-6-ONE KOH EN 

分 类 号：O6[理学—化学]