依普黄酮对笼养蛋鸡骨质疏松症相关激素的影响  

The Effects of Ipriflavone on Relevant Hormone of the Cage Layer Osteoporosis

作　　者：马利芹[1] 杨永红[1] 利凯[1] 

机构地区：[1]河北北方学院动物科技学院,河北张家口075131

出　　处：《中国畜牧兽医》2011年第11期86-89,共4页China Animal Husbandry & Veterinary Medicine

基　　金：河北省自然基金(C2010001447);河北教育厅项目(2008410)

摘　　要：本试验选用200只24周龄健康海兰褐蛋鸡,随机分为4组:对照组(基础日粮中含钙3.55%)、低钙组(日粮含钙1.27%)、试验Ⅰ组(8mg依普黄酮/kg+低钙日粮)和试验Ⅱ组(20mg依普黄酮/kg+低钙日粮),观察依普黄酮对笼养蛋鸡骨质疏松症相关激素的影响。结果显示,各组血清中甲状旁腺激素(PTH)水平均呈上升趋势,60d时,与低钙组相比,试验Ⅰ组和试验Ⅱ组血清中PTH水平分别降低了6.12%(P<0.01)和7.05%(P<0.01);试验Ⅰ组和试验Ⅱ组血清中碱性磷酸酶(AKP)水平分别降低了23.72%(P<0.01)和25.08%(P<0.01);各组血清中降钙素(CT)水平在15～30d时均呈上升趋势,在30～60d时均呈下降趋势。整个试验期,试验组和低钙组血钙水平比对照组有所降低,但差异不显著;各组雌激素(E2)水平无显著差异。试验结果表明,在低钙日粮中添加依普黄酮能够显著调节蛋鸡体内钙代谢相关激素的浓度,促进钙离子向骨骼沉积,减少骨组织脱钙,缓解蛋鸡骨质疏松的程度。Two hundred,24 week-old health cage layers were chosen,and divided randomly into four groups ： the control group（containing calcium 3.55% in based diet）,the low calcium group（containing calcium 1.27% in low-calcium diet）,the test group 1（adding 8 mg/kg ipriflavone to low-calcium diet） and test group 2（adding 20 mg/kg ipriflavone to low-calcium diet）.The effects of ipriflavone on relevant hormone of cage layer osteoporosis（CLO） were observed.The results showed that serum PTH levels showed an upward trend in each group.On 60 days,compared with the low-calcium group,PTH of test group 1,2 significantly reduced 6.12% and 7.05%（P〈0.01）.On 60 days,compared with the low-calcium group,the activity of serum AKP of test group 1,2 significantly reduced 23.72% and 25.08%（P〈0.01）.In each group,the serum CT levels showed the upward trend in the 15 to 30 d,and the declining trend in the 30 to 60 d.The entire experimental period,compare with the control group,the serum calcium levels of experimental group and low calcium group decreased,but the difference was not significant.The serum E_2 levels were not significant difference in each group.The results suggested that the low calcium diets supplemented with ipriflavone can prominently adjust relevant hormone levels of calcium metabolism,and promote deposition of calcium ion to the bone,reduce bone demineralization and mitigate the degree of osteoporosis layers.

关 键 词：笼养蛋鸡骨质疏松症 依普黄酮 激素 

分 类 号：S857.16[农业科学—临床兽医学]