淫羊藿提取物对大鼠缺血再灌注损伤心肌酶活性的影响  

Effects of Herba Epimedii's Extraction on the Enzymes of Myocardial Tissue of Myocardial Ischemia-Reperfusion Injury in Rats

作　　者：杨明[1] 周玥[1] 

机构地区：[1]川北医学院附属医院,四川南充637000

出　　处：《亚太传统医药》2011年第6期26-27,共2页Asia-Pacific Traditional Medicine

摘　　要：在离体实验中,淫羊藿提取物可以显著降低离体心脏心率、心肌张力,同时使离体心脏灌流量增加,并能够缓解由垂体后叶素、异丙肾上腺素和结扎冠脉所致的心肌缺血,显示出心肌缺血保护作用[3]。本实验以维拉帕米作为阳性对照,主要在整体方面研究淫羊藿提取物对大鼠心肌缺血再灌注损伤后心肌细胞中几种关键酶活性及含量的改变。Previous experiments indicated that the Herba Empimedii had a protective effects on myocardial ischemia induced either by drugs（Including Pit and ISO）or by ligating the coronary artery,simultaneously it could increase the flow of perfusion in vitro heart.The purpose of my experiment is to investigate the protective effect on myocardial ischemia-reperfusion injury.

关 键 词：淫羊藿 缺血-再灌注损伤 肌酸激酶 丙二醛 超氧化物歧化酶 

分 类 号：R285.5[医药卫生—中药学]