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作 者:金晨[1]
机构地区:[1]山东省枣庄市妇幼保健院,山东枣庄277102
出 处:《中国医药指南》2011年第32期277-278,共2页Guide of China Medicine
摘 要:目的观察应用胰岛素泵持续皮下注射(CSⅡ)联合动态血糖监测系统(CGMS)对妊娠糖尿病的治疗效果及安全性。方法选取妊娠糖尿病患者34例。分为胰岛素泵持续皮下注射(CSⅡ)联合动态血糖监测系统(CGMS),和多次胰岛素皮下治疗组(MSⅡ组),"双C"组给予佩戴CGMS24小时以后,胰岛素泵持续皮下注射短效胰岛素三餐前大剂量;MSⅡ组给予三餐前注射短效胰岛素和睡前注射中效胰岛素。对比两组血糖控制值、胰岛素用量、达标时间、低血糖发生、剖宫产率、平均住院天数。结果在整个妊娠过程中,CSⅡ组和MSⅡ组相比,胰岛素用量减少(28.12±6.06 VS 38.34±6.89)U、血糖达标时间缩短(8.2±0.3 VS 10.7±0.4),而且低血糖发生率及剖宫产率也低,差异有统计学意义(P<0.05)。结论应用"双C"方案治疗对妊娠糖尿病的治疗效果及安全性比传统多次皮下注射胰岛素更加全面和有效。Objective To investigate the efficacy and security of CS Ⅱ in combination with CGMS in GDM patients. Methods 34 GDM patients were divided into double C group and MS Ⅱ group. CS Ⅱ was used after detected for 24hours by CGMS. Shot insulin was injected pre meal and medium insulin was injected before sleep in MS Ⅱ group. Glucose levels, dosage of insulin, time to reaching the standard, incidence of hypoglucose, cesarean rate and average days of hospitalization were compared between two groups. Results Compared with MS Ⅱ group, dosage of insulin, time to reaching the standard, incidence of hypoglucose and cesarean rate were lower in double C group. Conclusions Compared with MS Ⅱ, double C therapeutic scheme was more comprehensive and efficient.
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