Effect of Yiqi Bufei Recipe （益气补肺方） on Patients with Pulmonary Incompetence after Pneumonectomy  

作　　者：YANG Yong SHEN You-kui ZHOU Xing-ming FU Xiao-qing MAO Wei-min DONG Li-wen WANG Jun CHENG Gen-miao 

机构地区：[1]Hangzhou Hospital of Traditional Chinese Medicine, Hangzhou （310007）, China [2]Zhejiang Provincial Hospital of Oncology, Hangzhou （310022）, China

出　　处：《Chinese Journal of Integrative Medicine》2011年第12期898-902,共5页中国结合医学杂志（英文版）

基　　金：Supported by Special Items of Traditional Chinese Medicine Sciences and Technology of State Administration of Traditional Chinese Medicine （No. 06-07LB10）

摘　　要：Objective： To study the effect of Yiqi Bufei Recipe （益气补肺方, YBR） on surgical tolerability, pulmonary compensatory function and post-operation rehabilitation in patients with pulmonary incompetence （PI） after pneumonectomy. Methods： YBR intervention was applied to 60 patients with PI after pneumonectomy （as test group）, the pulmonary and cardiac functions changes before and after operation, occurrence of postoperative complications, mortality, and the number of hospitalization days and intensive care unit （ICU） confinement period were observed. Meantime, for the negative and positive controls, the same parameters were observed comparatively in 60 patients with normal lung function, and in 60 patients with PI undergoing a similar operation but untreated with Chinese herbs. Results： Lung function in the test group showed insignificant change before and after operation （P〉0.05）, while significant decrease was seen in the two control groups （P〈0.05）. Furthermore, the incidences of post-operation complications and mortality as well as the number of hospitalization days and the ICU confinement period in the test group were significantly lower than those in the positive control group respectively （P〈0.05）. Conclusion： YBR could relieve lung injury after pneumonectomy, improve surgical tolerability, reduce the length of postoperative hospitalization days and ICU confinement period, and lower the incidence of postoperative complications and mortality in patients with PI after pneumonectomy.Objective： To study the effect of Yiqi Bufei Recipe （益气补肺方, YBR） on surgical tolerability, pulmonary compensatory function and post-operation rehabilitation in patients with pulmonary incompetence （PI） after pneumonectomy. Methods： YBR intervention was applied to 60 patients with PI after pneumonectomy （as test group）, the pulmonary and cardiac functions changes before and after operation, occurrence of postoperative complications, mortality, and the number of hospitalization days and intensive care unit （ICU） confinement period were observed. Meantime, for the negative and positive controls, the same parameters were observed comparatively in 60 patients with normal lung function, and in 60 patients with PI undergoing a similar operation but untreated with Chinese herbs. Results： Lung function in the test group showed insignificant change before and after operation （P〉0.05）, while significant decrease was seen in the two control groups （P〈0.05）. Furthermore, the incidences of post-operation complications and mortality as well as the number of hospitalization days and the ICU confinement period in the test group were significantly lower than those in the positive control group respectively （P〈0.05）. Conclusion： YBR could relieve lung injury after pneumonectomy, improve surgical tolerability, reduce the length of postoperative hospitalization days and ICU confinement period, and lower the incidence of postoperative complications and mortality in patients with PI after pneumonectomy.

关 键 词：Chinese medicine Yiqi Bufei Recipe pulmonary incompetence PNEUMONECTOMY 

分 类 号：S858.292[农业科学—临床兽医学] X503.1[农业科学—兽医学]