社区美沙酮维持治疗药瘾患者疗效的评估分析  

Evaulation of the community methadone maintenance treatment in Lianyungang City

作　　者：孙庆元[1] 章以法 张晶[1] 徐敏[1] 陈国红[2] 

机构地区：[1]连云港市第四人民医院社区美沙酮维持治疗门诊,江苏连云港222000 [2]江苏省疾病预防控制中心性病艾滋病防制所,江苏南京210009

出　　处：《南京医科大学学报（自然科学版）》2011年第10期1471-1475,共5页Journal of Nanjing Medical University(Natural Sciences)

摘　　要：目的:评估连云港市社区美沙酮维持治疗门诊药瘾患者接受口服美沙酮治疗的效果。方法:对2009年12月31日以前参加治疗的480例药瘾患者进行了为期1年的随访,其中207例患者以一对一问卷调查的方式完成了基线、6个月及1年的评估。结果:门诊患者治疗保持率达48.96%。随着治疗时间的延长,患者就业比例较基线时增加(P<0.05),与家人一同居住的比例增加(P<0.05),社会功能与家庭功能逐步恢复。3个时间段内患者使用海洛因的比例、注射吸毒行为与共用注射针具的比例有显著性差异(P<0.05)。除2例患者在入组治疗前已感染HIV以外,治疗过程中无HIV抗体阳转病例。结论:社区美沙酮维持治疗门诊提供的医疗服务在减少患者毒品使用的同时减少了艾滋病感染相关注射行为,其家庭功能与职业功能得到有效恢复,但需针对不同个案开展进一步的社会心理支持。Objective： To study the effect of community methadone maintenance treatment among patients who had addicted to heroin in Lianyungang City.Methods： 480 patients who had entered the treatment center by the end of December 31,2009 were followed up for 1 year.Face-to-face investigation was conducted among 207 patients for baseline,6-month and 1-year evaluation with questionnaire by the doctor.The content is concerned to heroin abuse,present job status and social function.Results： The retention rate was 48.96% in this study.Along with the length of treatment,the proportion of both having a job and living with relatives increased in the two evaluation groups（P 0.05）.Social function and family function were recovered gradually.Heroin abuse behavior,injection and syringe-sharing behavior were statistically difference among the three groups（P 0.05）.With the exception of 2 HIV positive cases that had been infected before the program was initiated,none of the HIV negative patient had seroconverted to the HIV positive status.Conclusion： Services provided by Community-based methadone maintenance treatment was thought to reduce drug-use and HIV related high risk behaviors such as sharing syringes.Family function and social function were improved after treatment.In-depth counseling and support from the society were urgently required aimed at the individual cases.

关 键 词：美沙酮维持治疗 艾滋病 效果 

分 类 号：R512.91[医药卫生—内科学]