盐酸催化苯并-15-冠-5酰腙衍生物的合成反应研究  

Study on Synthesis of Benzo-15-crown-5 Hydrazone Derivatives Catalyzed by Concentrated Hydrogen Chloride

作　　者：周艳青[1] 王青山 唐蓉萍[1] 吕维华[1] 伍家卫[1] 

机构地区：[1]兰州石化职业技术学院石油化学工程系,甘肃兰州730060 [2]中国石油西南润滑油销售分公司,四川成都610000

出　　处：《化工技术与开发》2011年第11期10-11,共2页Technology & Development of Chemical Industry

基　　金：甘肃省省属高校基本科研业务费资助项目(甘财教2009-192)

摘　　要：以乙醇为溶剂,4′-乙酰基苯并-15-冠-5和酰肼为反应物,浓盐酸作催化剂,在回流条件下合成了7个冠醚化的酰腙,产品经元素分析、IR和1HNMR表征,确定为目标化合物。结果表明,浓盐酸催化下的反应能够在1h内完成,并且产率在90%左右,是合成该类化合物的高效催化剂。A series of benzo-15-crown-5 hydrazone derivatives were synthesized under reflux condition.The structure of these compounds were characterized by elemental analysis,IR and 1HNMR.The reaction only needed 1h to proceed catalyzed by concentrated hydrogen chloride（HCl）,and the yields of the product reached 90%.It was clear that HCl was an efficient catalysis for the synthesis of this kind of fine chemicals.

关 键 词：苯并-15-冠-5 酰腙 浓盐酸 

分 类 号：O621.3[理学—有机化学]