黄芪注射液治疗早产儿脑室周围白质软化的临床疗效观察  

Astragalus injection in treating periventricular leukomalacia in premature infants

作　　者：徐桂霞[1] 战美丽[1] 冯玉梅[1] 

机构地区：[1]泰山医学院附属聊城市第二人民医院新生儿科,山东临清252601

出　　处：《中国实用医刊》2011年第23期12-14,共3页Chinese Journal of Practical Medicine

摘　　要：目的探讨黄芪注射液治疗早产儿脑室周围白质软化的临床疗效。方法将2006年10月至2010年9月泰山医学院附属聊城市第二人民医院新生儿病房收治的85例确诊为脑室周围白质软化的早产儿随机分为两组。Ⅰ组（对照组）42倒，采用保暖、吸氧、控制感染、纠正酸碱及电解质紊乱，维持正常血糖、血压、血气等常规治疗；Ⅱ组43例，在常规治疗基础上加用黄芪注射液静脉注射。定期观察和随诊颅脑B超的变化，进行统计学分析。结果①黄芪注射液治疗组治疗有效率优于对照组，两组比较差异有统计学意义（P〈0．05）；②分别于校正胎龄40、41周进行2次新生儿神经行为（NBNA）评分，黄芪注射液治疗组明显优于对照组，差异有统计学意义（P〈0．01）。结论黄芪注射液治疗早产儿脑室周围白质软化疗效显著，可改善预后。Objective To investigate the clinical effects of astragalus injection in treating periventricular leukomalacia in premature infants. Methods Eighty -five premature infants with periventricular leukomalacia who were in newborn intensive care uint of our hospital from October 2006 to September 2010 were randomly divided into the control group （42 cases）and astragalus injection group （43 cases）. The cases in control group（ group Ⅰ） were given routine treatment. The cases in astragalus injection group（ group Ⅱ） were given astragalus injection on the base of the control group. The differences of B ultrasonic were observed and were analyzed by statistics. Results ①The effective rate in astragalus injection group was obviously higher than that in control group. There were significant difference between the two groups by statistics （ P 〈 0.05 ）. ②Neonatal behavioral neurological assessment （NBNA） was evaluated when age of the newborns were 40 weeks and 41 weeks. There was obvious difference between the two groups （ P 〈 0.01 ）. Conclusions Astragalus injection have obvious effect on treating periventricular leukomalacia in premature infants and can improve the prognosis.

关 键 词：黄芪注射液 早产儿 脑室周围白质软化 

分 类 号：R272[医药卫生—中医儿科学]