言语诱发听性脑干反应的主波特性  

The Characteristics of Feature Peaks in Speech Evoked Auditory Brainstem Responses

作　　者：符秋养[1,2] 梁勇[1] 王涛[3] 戴红亚 

机构地区：[1]南方医科大学南方医院耳鼻咽喉-头颈外科,广州510515 [2]广东省第二人民医院耳鼻咽喉-头颈外科 [3]南方医科大学生物医学工程学院

出　　处：《听力学及言语疾病杂志》2011年第6期497-501,共5页Journal of Audiology and Speech Pathology

基　　金：国家自然科学基金项目(61172033);广东省科技计划项目(2010B031600099)联合资助

摘　　要：目的探讨正常成人言语诱发听性脑干反应(speech evoked auditory brainstem response,speech-ABR)主波的电生理特性。方法记录64例正常成人右耳的speech-ABR,分析主波的极性、潜伏期及幅值及其与性别、年龄的相关性。结果 speech-ABR的主波主要为正极性;除E波极性与性别显著相关外,其他主波极性的性别和年龄差异无统计学意义。V波和A波潜伏期女性较男性显著缩短,V波幅值女性较男性显著增大;而两者潜伏期和幅值的年龄差异无统计学意义。在C、D、E、F和O波中,两种极性的潜伏期差异(除E波和O波外)以及幅值差异无统计学意义;而其潜伏期和幅值的性别和年龄差异亦无统计学意义。结论 speech-ABR各主波的潜伏期和幅值受极性、性别和年龄差异的影响较小,具有较高的稳定性,是言语感知机制基础及临床研究的良好指标。Objective To explore the characteristics of feature peaks in speech evoked auditory brainstem responses（speech-ABRs） from healthy Chinese adults so as to promote the applications in clinical researches.Methods Speech-ABRs to speech syllables /da/ of 64 subjects were recorded from right ears.Polarities,latencies and amplitudes of the feature peaks labeled as peak-V,A,C,D,E,O etc,were compared and their correlation with gender and age were analyzed statistically.Results The main polarities of feature peaks were positive and their correlation with gender and age were no significant respectively（except peak E）.Significant delays of peak-V and-A latencies and increases of peak-V amplitude were observed for male with respect to female.There was no significant difference of latencies and amplitudes of peak-V and peak-A for age sensitivity,and no significant difference of latencies and amplitudes of peak-C,-D,-E,-O and-F for gender and age sensitivities,while latencies of peak-E and-O showed significantly difference for two polarities.Conclusion The latencies and amplitudes of feature peaks of speech-ABR are stable,and insensitive to polarity,gender and age,which can be used as indicators in the study of speech perception mechanism and clinical research.

关 键 词：言语 听性脑干反应 极性 性别 年龄 

分 类 号：R764.04[医药卫生—耳鼻咽喉科]