25例糖耐量异常合并OSAHS孕妇雌三醇和孕酮水平研究  

The levels of estriol and progesterone in IGT pregnant women combined with OSAHS in 25 cases

作　　者：施志敏[1] 李涛平[1] 

机构地区：[1]南方医科大学南方医院睡眠中心,广州510515

出　　处：《重庆医学》2011年第32期3272-3273,共2页Chongqing medicine

基　　金：国家自然科学基金资助项目(30471720);广东省自然科学基金资助项目(04020458)

摘　　要：目的探讨睡眠呼吸暂停低通气综合征(OSAHS)合并糖耐量异常(IGT)孕妇雌三醇和孕酮水平。方法选择OS-AHS合并IGT孕妇25例(IGT+OSAHS组),单纯IGT孕妇35例(IGT组),对两组患者进行多导睡眠监测,监测呼吸暂停低通气指数(AHI)、夜间最低血氧饱和度(LSpO2),并测定比较雌三醇、孕酮水平。结果与IGT组相比,IGT+OSAHS组AHI明显升高,而LSpO2明显降低(P<0.05);两组患者雌三醇、孕酮比较,差异无统计学意义(P>0.05)。结论 IGT孕妇其OSAHS的发生可能与雌三醇和孕酮水平无关。Objective To investigate the level of progestogen in impaired glucose tolerance（IGT） pregnant women combined with obstructive sleep apnea hypopnea syndrome（OSAHS）.Methods Twenty-five IGT pregnant women combined with OSAHS（IGT＋OSAHS group）and thirty-five IGT pregnant women（IGT group） were randomly selected to record all night polysomnography（PSG）,and recorded apnea hypopnea index（AHI） and LSpO2.The levels of estriol and progesterone were measured.Results Compared with IGT group,AHI and decreased and LSpO2 increased significantly in IGT＋OSAHS group.The levels of estriol and progesterone in IGT＋OSAHS group were not significantly different with IGT group（P〈0.05）.Conclusion The level of progestogen in IGT pregnancy women combined with OSAHS is not related to pathogenesis of OSAHS.

关 键 词：睡眠呼吸暂停综合征 妊娠 孕激素类 糖耐量异常 

分 类 号：R766[医药卫生—耳鼻咽喉科]