有氧运动与力竭游泳运动对小鼠免疫功能的影响  

Effects of Aerobic and Exhausted Exercise on the Immune Function in Mice

作　　者：刘宏鹏[1] 赵志芳[1] 陶虹[1] 刘红梅[1] 芦宁清[1] 周旭[1] 李光华[1] 

机构地区：[1]宁夏医科大学,银川750004

出　　处：《宁夏医科大学学报》2011年第10期916-919,共4页Journal of Ningxia Medical University

基　　金：宁夏自然科学基金(NZ10111);宁夏医科大学面上项目(XM200802)

摘　　要：目的研究有氧运动与力竭运动对小鼠免疫功能的影响。方法雄性昆明种小鼠按体重随机分为空白对照组、有氧运动组和力竭运动组,分别进行有氧与力竭游泳运动,观察两种运动负荷对小鼠体重增长、免疫器官相对重量、腹腔巨噬细胞吞噬率、溶菌酶含量、抗体效价、耳肿指数的影响。结果有氧运动组小鼠胸腺和脾脏指数、腹腔巨噬细胞吞噬率、溶菌酶含量、抗体效价、耳肿指数均高于空白对照组(P<0.05);力竭运动组小鼠体重增长、胸腺和脾脏指数、腹腔巨噬细胞吞噬率、溶菌酶含量、抗体效价、耳肿指数均低于空白对照组和有氧运动组(P<0.05)。结论有氧运动能增强小鼠免疫功能而,力竭运动则降低小鼠免疫功能。Objective To investigate the effects of aerobic and exhausted swimming exercise on immune function in mice.Methods Male Kunming mice were chosen and divided randomly into three groups including controls,aerobic and exhausted swimming exercise groups.Aerobic and exhausted swimming exercise model was employed to observe the effects of two type of the exercise load on the weight gain,the weight of immunity organs,the phagocytosis rate of macrophagus in abdominal cavity,the content of serum murammidase,antibody potency and ear swelling index.Results The weight of immunity organs,the phagocytosis rate of macrophagus in abdominal cavity,the content of serum murammidase,antibody potency and ear swelling index which were significantly higher than those in control group（P0.05）.Comparing with the group of control and aerobic,the body weight,the weight of immunity organs,the phagocytosis rate of macrophagus in abdominal cavity,the content of serum murammidase,antibody potency and ear swelling index significantly decreased in exhausted mice（P0.05）.Conclusion Exhausted exercise can depress the immune function,whereas aerobic exercise can enhance the immune function.

关 键 词：有氧运动 力竭运动 免疫功能 小鼠 

分 类 号：R87[医药卫生—运动医学]